3-(2,4'-Dichlorobenzhydryloxy)azetidine hydrochloride → 3-[2-Trifluoromethyl-4'-(methylthio)benzhydryloxy]azetidine hydrochloride
반응식
C([N:14]1[CH2:17][CH:16]([O:18][CH:19]([C:30]2[CH:35]=[CH:34][C:33]([S:36][CH3:37])=[CH:32][CH:31]=2)[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=2[C:26]([F:29])([F:28])[F:27])[CH2:15]1)(C1C=CC=CC=1)C1C=CC=CC=1.Cl.[Cl:39]C1C=CC=CC=1C(OC1CNC1)C1C=CC(Cl)=CC=1>>[ClH:39].[F:29][C:26]([F:27])([F:28])[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=1[CH:19]([O:18][CH:16]1[CH2:17][NH:14][CH2:15]1)[C:30]1[CH:35]=[CH:34][C:33]([S:36][CH3:37])=[CH:32][CH:31]=1참가 물질
3
실험 절차
This material was prepared from 1-benzhydryl-3-[2-(trifluoromethyl)-4′-(methylthio)benzhydryloxy]azetidine (117) (8.7 mmol) using the procedure described for compound (9) (2.29 g, 68%).
출처 및 근거
- ORD 기록
- ord-c59e34abcd84451390d37be085dee1e1
- 출처 데이터셋
- uspto-grants-2009_03