Isocyanate → 3-[2-(trifluoromethyl)-4'-(methylthio)benzhydryloxy]-N-(benzyl)-azetidine-1-carboxamide
반응식
Cl.[F:2][C:3]([F:25])([F:24])[C:4]1[CH:23]=[CH:22][CH:21]=[CH:20][C:5]=1[CH:6]([O:15][CH:16]1[CH2:19][NH:18][CH2:17]1)[C:7]1[CH:12]=[CH:11][C:10]([S:13][CH3:14])=[CH:9][CH:8]=1.[N-:26]=[C:27]=[O:28]>>[F:25][C:3]([F:2])([F:24])[C:4]1[CH:23]=[CH:22][CH:21]=[CH:20][C:5]=1[CH:6]([O:15][CH:16]1[CH2:19][N:18]([C:27]([NH:26][CH2:3][C:4]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:5]=2)=[O:28])[CH2:17]1)[C:7]1[CH:12]=[CH:11][C:10]([S:13][CH3:14])=[CH:9][CH:8]=1참가 물질
3
실험 절차
This material was prepared from 3-[2-trifluoromethyl-4′-(methylthio)benzhydryloxy]azetidine hydrochloride (118) and the corresponding isocyanate using the procedure described for compound (10).
출처 및 근거
- ORD 기록
- ord-4a4b1738bee54d4ea5525b7f8764cae7
- 출처 데이터셋
- uspto-grants-2009_03