4-Fluoro-2-(trifluoromethyl)benzaldehyde → 2-(Trifluoromethyl)-4-fluoro-4'-chlorobenzhydrol

HRID 1785675

반응식

HRID 1785675 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([Mg]Br)=[CH:4][CH:3]=1.[F:10][C:11]1[CH:18]=[CH:17][C:14]([CH:15]=[O:16])=[C:13]([C:19]([F:22])([F:21])[F:20])[CH:12]=1.ClC1C=C(Cl)C=CC=1C(O)C1C=CC(Cl)=CC=1>>[F:21][C:19]([F:20])([F:22])[C:13]1[CH:12]=[C:11]([F:10])[CH:18]=[CH:17][C:14]=1[CH:15]([OH:16])[C:5]1[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=1

참가 물질

4

반응물 3

HCID 5229404-Fluoro-2-(trifluoromethyl)benzaldehydeHCID 225654352,4,4'-TrichlorobenzhydrolHCID 178478191HCID 178478191, 화합물

생성물 1

HCID 689078022-(Trifluoromethyl)-4-fluoro-4'-chlorobenzhydrol

실험 절차

This material was prepared from 4-chlorophenylmagnesium bromide (28.6 mmol) and 4-fluoro-2-(trifluoromethyl)benzaldehyde (26.0 mmol) using the procedure described for compound (2) (6.04 g, 76%).

출처 및 근거

ORD 기록
ord-49b4dd7ebec8402a9268ee21bc27c2de
출처 데이터셋
uspto-grants-2009_03
특허 번호
US07504522B2

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