Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Methoxyacetohydrazide → 9-Chloro-2-methoxymethyl-6H-[1,2,4]triazolo[1,5-c]quinazolin-5-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Methoxyacetohydrazide | HCID 2759532 | — |
| 반응물 | Ethyl 4-chloro-2-cyanophenylcarbamate | HCID 21779762 | — |
| 생성물 | 9-Chloro-2-methoxymethyl-6H-[1,2,4]triazolo[1,5-c]quinazolin-5-one | HCID 136347869 | 88% |
반응 단계
As described for example 1a) (4-chloro-2-cyano-phenyl)-carbamic acid ethyl ester (71.0 g, 316 mmol) using methoxymethyl-carboxylic acid hydrazide instead of cyclopropane-carboxylic acid hydrazide, was converted to the title compound (73.9 g, 88%) which was obtained as a yellow solid. MS: m/e=264.9 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07507729B2 |
| 출처 데이터셋 | uspto-grants-2009_03 |
| ORD ID | ord-966f88043c0a4b97b0f02e8322057c1f |
| 출처 메모 | uspto-grants-2009_03 |