3-Methyl-4-((6-methylpyridin-3-yl)oxy)aniline → 5-methyl-N-{3-methyl-4-[(6-methylpyridin-3-yl)oxy]phenyl}-5H-pyrrolo[3,2-d]pyrimidin-4-amine
반응식
Cl[C:2]1[C:3]2[N:10]([CH3:11])[CH:9]=[CH:8][C:4]=2[N:5]=[CH:6][N:7]=1.[CH3:12][C:13]1[CH:14]=[C:15]([CH:17]=[CH:18][C:19]=1[O:20][C:21]1[CH:22]=[N:23][C:24]([CH3:27])=[CH:25][CH:26]=1)[NH2:16]>CN1CCCC1=O>[CH3:11][N:10]1[C:3]2[C:2]([NH:16][C:15]3[CH:17]=[CH:18][C:19]([O:20][C:21]4[CH:22]=[N:23][C:24]([CH3:27])=[CH:25][CH:26]=4)=[C:13]([CH3:12])[CH:14]=3)=[N:7][CH:6]=[N:5][C:4]=2[CH:8]=[CH:9]1참가 물질
4
실험 절차
To a solution of 4-chloro-5-methyl-5H-pyrrolo[3,2-d]pyrimidine (100 mg) in 1-methyl-2-pyrrolidone (1.0 mL) was added 3-methyl-4-[(6-methylpyridin-3-yl)oxy]aniline (192 mg). The title compound (106 mg) was obtained as white powder crystals by the reaction in the same manner as in Example 39 (ii).