3-Acetylbenzoic acid → 1-(3-(Pyrrolidine-1-carbonyl)phenyl)ethanone

반응식

O[C:2]1[CH:7]=[CH:6][C:5]([C:8]([N:10]2[CH2:14][CH2:13][CH2:12][CH2:11]2)=[O:9])=[CH:4][C:3]=1[C:15](=[O:17])[CH3:16].C(C1C=C(C=CC=1)C(O)=O)(=O)C>>[N:10]1([C:8]([C:5]2[CH:4]=[C:3]([C:15](=[O:17])[CH3:16])[CH:2]=[CH:7][CH:6]=2)=[O:9])[CH2:14][CH2:13][CH2:12][CH2:11]1

참가 물질

반응물 2

HCID 2203243-Acetylbenzoic acid

HCID 576031221-[2-Hydroxy-5-(pyrrolidine-1-carbonyl)-phenyl]-ethanone

생성물 1

HCID 689220051-(3-(Pyrrolidine-1-carbonyl)phenyl)ethanone

실험 절차

The title intermediate was synthesized as described for Compound 18 except 3-acetylbenzoic acid was used instead of 3-acetyl-4-hydroxy benzoic acid.

출처 및 근거

ORD 기록: ord-646d0f843ba64899b93369d2fcf73691
출처 데이터셋: uspto-grants-2009_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07511145B2

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