1-Dodecanol → n-Dodecyl 2-[4-(5-Trifluoromethyl-2-Pyridinyloxy) Phenoxy]Propanoate

HRID 1788860노트

반응식

HRID 1788860 반응식
[CH2:1]([OH:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C(N(CC)CC)C.[F:21][C:22]([F:43])([F:42])[C:23]1[CH:24]=[CH:25][C:26]([O:29][C:30]2[CH:41]=[CH:40][C:33]([O:34][CH:35]([CH3:39])[C:36](Cl)=[O:37])=[CH:32][CH:31]=2)=[N:27][CH:28]=1>C1(C)C=CC=CC=1>[F:42][C:22]([F:21])([F:43])[C:23]1[CH:24]=[CH:25][C:26]([O:29][C:30]2[CH:41]=[CH:40][C:33]([O:34][CH:35]([CH3:39])[C:36]([O:13][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])=[O:37])=[CH:32][CH:31]=2)=[N:27][CH:28]=1

참가 물질

5

반응물 3

HCID 81931-DodecanolHCID 8471TriethylamineHCID 130552202-(4-{[5-(Trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoyl chloride

생성물 1

HCID 20189152n-Dodecyl 2-[4-(5-Trifluoromethyl-2-Pyridinyloxy) Phenoxy]Propanoate

시약·촉매·용매 1

HCID 1140Toluene용매2회

반응 조건

온도
10 °C

실험 절차

n-Dodecanol(2.5 grams; 0.134mol), toluene (80 ml) and triethylamine (5 ml) were placed into a 300 ml, 3-necked glass reaction flask equipped with stirrer, thermometer, reflux condenser, and nitrogen line. 2-[4-(5-trifluoromethyl-2-pyridinyloxy)phenoxy]propanoic acid chloride (4.45 grams; 0.0125 mol) in toluene (30 ml) was added dropwise to the reaction mixture with stirring at a temperature of about 10° C. The temperature of the reaction mixture was allowed to rise to room temperature and stirred overnight.

후처리

  1. customequipped with stirrer
  2. temperaturethermometer, reflux condenser
  3. customto rise to room temperature
  4. stirringstirred overnight

출처 및 근거

ORD 기록
ord-43deab324a3240d394a7343e641e646e
출처 데이터셋
uspto-grants-1987_08
특허 번호
US04685960

반응 노트

불러오는 중…