Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1788907생성일: 2026년 10월 26일
1-Piperazinecarboxylic acid, ethyl ester → 4-(1,4-Dihydro-3-methyl-1, 4-dioxo-2-naphthalenyl)-1-piperazinecarboxylic acid, ethyl ester
https://huagongshe.com/reaction/1788907
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1-Piperazinecarboxylic acid, ethyl ester | HCID 8431 | — |
| 반응물 | 2,3-Epoxy-2-methyl-1,4-naphthoquinone | HCID 85845 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4-(1,4-Dihydro-3-methyl-1, 4-dioxo-2-naphthalenyl)-1-piperazinecarboxylic acid, ethyl ester | HCID 14278765 | 30.5% |
반응 단계
A mixture of 1.88 g of 2,3-epoxy-3-methyl-1,4-naphthoquinone, 3.16 g of piperazinecarboxylic acid, ethyl ester and 100 ml of absolute ethanol was stirred for 12 hours at 50° C. The solvent was then removed and the remainder filtered through a one inch plug of silica gel and eluted with chloroform. The eluate was evaporated, giving 1 g of the desired product as a viscous red oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US04686220 |
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| 출처 데이터셋 | uspto-grants-1987_08 |
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| ORD ID | ord-bd93f5c31e3a4d1182f4de13828044bc |
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| 출처 메모 | uspto-grants-1987_08 |
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