HCID 13912877, 화합물 → HCID 20189753, 화합물

HRID 1789081노트

반응식

HRID 1789081 반응식
[CH3:1][N:2]([CH3:17])[C:3](=[O:16])[C:4]1[CH:9]=[C:8]([NH2:10])[C:7]([N+:11]([O-])=O)=[CH:6][C:5]=1[O:14][CH3:15]>C(O)C.[C].[Pd]>[CH3:17][N:2]([CH3:1])[C:3](=[O:16])[C:4]1[CH:9]=[C:8]([NH2:10])[C:7]([NH2:11])=[CH:6][C:5]=1[O:14][CH3:15]

참가 물질

4

반응물 1

HCID 13912877HCID 13912877, 화합물

생성물 1

HCID 20189753HCID 20189753, 화합물

시약·촉매·용매 2

HCID 178418390HCID 178418390, 화합물촉매HCID 702Ethanol용매

실험 절차

A suspension of 3.62 g of N,N-dimethyl 5-amino-2-methoxy4-nitrobenzamide and 150 mg of 10 % palladium carbon in 140 ml of ethanol was stirred at 70°-80° C. under a hydrogen atmosphere. After the absorption of hydrogen was completed, the catalyst was removed by filtration, and the filtrate was evaporated to dryness to give crude N,N-dimethyl 4,5-diamino2-methoxybenzamide, which was then dissolved in 30 ml of tetrahydrofuran.

후처리

  1. customAfter the absorption of hydrogen
  2. customthe catalyst was removed by filtration
  3. customthe filtrate was evaporated to dryness

출처 및 근거

ORD 기록
ord-25d717c20516453d9c35a1cb80195294
출처 데이터셋
uspto-grants-1987_08
특허 번호
US04686292

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