Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrogen Bromide → N-(4-piperidinylmethyl)-2-benzothiazolamine dihydrobromide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrogen Bromide | HCID 260 | — |
| 반응물 | 1-acetyl-N-(2-benzothiazolyl)-4-piperidinemethanamine | HCID 14048944 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | N-(4-piperidinylmethyl)-2-benzothiazolamine dihydrobromide | HCID 14048948 | 79% |
반응 단계
A mixture of 140 parts of 1-acetyl-N-(2-benzothiazolyl)-4-piperidinemethanamine and 1500 parts of a hydrobromic acid solution 24% in water was stirred and refluxed for 5 hours. The reaction mixture was evaporated and the residue was suspended in boiling ethanol. After cooling, the product was filtered off and dried, yielding 122 parts (79%) of N-(4-piperidinylmethyl)-2-benzothiazolamine dihydrobromide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04689330 |
| 출처 데이터셋 | uspto-grants-1987_08 |
| ORD ID | ord-c9b16aa6f74749a99eb7aab43a37c592 |
| 출처 메모 | uspto-grants-1987_08 |