반응식
[N:1]1([CH2:6][CH2:7][N:8]2[C:16]3[C:11](=[CH:12][CH:13]=[C:14]([NH2:17])[CH:15]=3)[CH:10]=[N:9]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[O:18]([C:25]1[CH:26]=[C:27]([CH2:31][C:32](O)=[O:33])[CH:28]=[CH:29][CH:30]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[O:18]([C:25]1[CH:26]=[C:27]([CH2:31][C:32]([NH:17][C:14]2[CH:15]=[C:16]3[C:11]([CH:10]=[N:9][N:8]3[CH2:7][CH2:6][N:1]3[CH2:5][CH2:4][CH2:3][CH2:2]3)=[CH:12][CH:13]=2)=[O:33])[CH:28]=[CH:29][CH:30]=1)[C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1참가 물질
3
실험 절차
According to the procedure for Example 49, 1-(2-pyrrolidin-1-yl-ethyl)-1H-indazol-6-ylamine and (3-phenoxy-phenyl)-acetic acid were processed to provide the title compound. 1H NMR (500 MHz, DMSO-d6) δ ppm 1.82 (m, 2 H), 1.99 (m, 2 H), 3.03 (m, 2 H), 3.51 (m, 2 H), 3.68 (m, 4 H), 4.66 (t, J=6.24 Hz, 2 H), 6.89 (m, 1 H), 7.03 (m, 3 H), 7.12 (m, 3 H), 7.37 (m, 3 H), 7.72 (m, 1 H), 8.08 (s, 1 H), 8.26 (s, 1 H), 9.55 (br s, N H); MS (DCI/NH3) m/z 441 (M+H)+.
출처 및 근거
- ORD 기록
- ord-c1b40672e9364bf7ade1762da79c3923
- 출처 데이터셋
- uspto-grants-2006_07
- 특허 번호
- US07071182B2
연결된 노트
불러오는 중…