Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,4-Difluorophenethyl bromide → 1-[1-(2,4-Difluorophenethyl)-piperidin-4-yl]-6-chloro-7-azaindoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,4-Difluorophenethyl bromide | HCID 11298989 | — |
| 반응물 | 1-(Piperidin-4-yl)-6-chloro-7-azaindoline | HCID 22038287 | — |
| 생성물 | 1-[1-(2,4-Difluorophenethyl)-piperidin-4-yl]-6-chloro-7-azaindoline | HCID 22038121 | 7.8% |
반응 단계
1-(Piperidin-4-yl)-6-chloro-7-azaindoline (0.5 g) and 2,4-difluorophenethyl bromide (0.43 g) were treated as in Example 2 to give the hydrochloride (74 mg) of the title compound as a brown powder (yield: 7.8%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07071201B2 |
| 출처 데이터셋 | uspto-grants-2006_07 |
| ORD ID | ord-1d981b97ad054fe78432ba569c0c0283 |
| 출처 메모 | uspto-grants-2006_07 |