p-Toluenesulfonic acid → Allyl-(1-methyl-pent-4-enylidene)-amine Allyl-(1-methyl-pent-4-enyl)-amine

HRID 1790607노트

반응식

HRID 1790607 반응식
[CH3:1][C:2](=O)[CH2:3][CH2:4][CH:5]=[CH2:6].[CH2:8]([NH2:11])[CH:9]=[CH2:10].[C:12]1(C)[CH:17]=[CH:16][C:15](S(O)(=O)=O)=[CH:14][CH:13]=1>C(Cl)Cl>[CH2:8]([NH:11][CH:2]([CH3:1])[CH2:3][CH2:4][CH:5]=[CH2:6])[CH:9]=[CH2:10].[CH2:8]([N:11]=[C:16]([CH3:15])[CH2:17][CH2:12][CH:13]=[CH2:14])[CH:9]=[CH2:10]

참가 물질

5

반응물 3

HCID 6101p-Toluenesulfonic acidHCID 7853AllylamineHCID 79895-Hexene-2-one

생성물 1

HCID 22036684Allyl-(1-methyl-pent-4-enylidene)-amine Allyl-(1-methyl-pent-4-enyl)-amine

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

Hex-5-en-2-one (9.8 g, 11.6 ml, 100 mmol) was added to a stirred solution of allylamine (8.55 mmol, 11.25 ml, 150 mmol), 4 Angstrom molecular sieves (52 g), and p-toluene sulfonic acid (10 mg) in CH2Cl2 (200 ml) and was stirred overnight. The reaction mixture was concentrated in vacuo by rotary evaporation and was used in the next reaction without further purification (13 g, 95%). Electrospray mass spec: M+H+=137.9

후처리

  1. concentrationThe reaction mixture was concentrated in vacuo by rotary evaporation
  2. customwas used in the next reaction without further purification (13 g, 95%)

출처 및 근거

ORD 기록
ord-09f4020875874426a74d475a4e4e5dbd
출처 데이터셋
uspto-grants-2006_07
특허 번호
US07071184B2

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