Morpholine → 4-(6-Bromoquinolin-4-yl)morpholine

HRID 1792434노트

반응식

HRID 1792434 반응식
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][CH:6]=[C:5]2Cl.[NH:13]1[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1>>[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][CH:6]=[C:5]2[N:13]1[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1

참가 물질

3

반응물 2

HCID 8083MorpholineHCID 51395376-Bromo-4-chloroquinoline

생성물 1

HCID 220314084-(6-Bromoquinolin-4-yl)morpholine

실험 절차

122 mg 6-bromo-4-chloroquinoline and 0.13 mL morpholine were reacted by the same method as in Production Example 74 to give 68 mg of the title compound as a colorless oil.

출처 및 근거

ORD 기록
ord-a1988d1ba7504d79b97782eddbccf622
출처 데이터셋
uspto-grants-2006_07
특허 번호
US07074801B1

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