Ethanol → Ethyl (2-methoxyethoxy)acetate

HRID 1792510노트

반응식

HRID 1792510 반응식
[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][C:7]([OH:9])=[O:8].S(=O)(=O)(O)O.[CH2:15](O)[CH3:16]>>[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][C:7]([O:9][CH2:15][CH3:16])=[O:8]

참가 물질

4

반응물 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 27642(2-Methoxyethoxy)acetic acid

생성물 1

HCID 9898912Ethyl (2-methoxyethoxy)acetate

실험 절차

150 mL solution of 10 g (2-methoxyethoxy)acetic acid and 1 mL conc. sulfuric acid in ethanol was heated for 3 hours under reflux, and then the solvent was removed. The resulting residue was diluted with ethyl acetate and washed with an aqueous saturated sodium bicarbonate solution and brine. The organic layer was dried over anhydrous sodium sulfate, and then the solvent was removed, whereby 9.5 g of the title compound (colorless oil) was obtained.

후처리

  1. temperatureunder reflux
  2. customthe solvent was removed
  3. additionThe resulting residue was diluted with ethyl acetate
  4. washwashed with an aqueous saturated sodium bicarbonate solution and brine
  5. dry with materialThe organic layer was dried over anhydrous sodium sulfate
  6. customthe solvent was removed

출처 및 근거

ORD 기록
ord-adb0227557f042d48c4b0bb45bdb7e7a
출처 데이터셋
uspto-grants-2006_07
특허 번호
US07074801B1

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