Oxalyl chloride → HCID 22024994, 화합물
반응식
[C:1](Cl)(=O)[C:2]([Cl:4])=[O:3].C([C:10]1C=[CH:13][N:12]([C:15]2[CH:24]=[CH:23][CH:22]=[C:21]3[C:16]=2[CH:17]=[CH:18][CH:19]=[N:20]3)[CH:11]=1)(O)=O>ClCCl>[ClH:4].[Cl:4][C:2]([C:1]1[CH:10]=[CH:11][N:12]([C:15]2[CH:24]=[CH:23][CH:22]=[C:21]3[C:16]=2[CH:17]=[CH:18][CH:19]=[N:20]3)[CH:13]=1)=[O:3]참가 물질
4
반응 조건
- 온도
- 22 °C
실험 절차
0.5 mL (5.73 mmol) of oxalyl chloride is added to a solution, cooled to a temperature in the region of 5° C., of 0.42 g (1.76 mmol) of 3-carboxy-1-(quinol-5-yl)-1H-pyrrole in 10 mL of dichloromethane under an argon atmosphere. After stirring at a temperature in the region of 22° C. for 15 hours, concentrating the reaction mixture to dryness under reduced pressure (2.7 kPa) gives 0.55 g of 3-chlorocarbonyl-1-(quinol-5-yl)-1H-pyrrole hydrochloride in the form of a cream-coloured solid which is used directly in the following step.