Piperidine → 1-Phenyl-3-(piperidin-1-yl)propan-1-amine

반응식

Br[CH2:2][CH2:3][CH:4]([NH:11]C(OC(C)(C)C)=O)[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.[NH:19]1[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1>>[C:5]1([CH:4]([NH2:11])[CH2:3][CH2:2][N:19]2[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]2)[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=1

참가 물질

반응물 2

HCID 8082Piperidine

HCID 22026034478538-78-2

생성물 1

HCID 137990911-Phenyl-3-(piperidin-1-yl)propan-1-amine

실험 절차

The procedure given in Example 2 except for the formation of salts was followed using 3-bromo-1-(tert-butoxycarbonyl)amino-1-phenyl propane and piperidine as reactants, instead of d-1-bromo-2-(tert-butoxycarbonyl)amino-3-phenyl propane and hexamethyleneimine to give 1-Phenyl-3-(1-piperidinyl)-n-propylamine.

출처 및 근거

ORD 기록: ord-ad1da34fdff74ffd8ff1cfc5f671ee2b
출처 데이터셋: uspto-grants-2006_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07078537B2

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