Oxalyl chloride → N-[2-(3-Dimethylamino-pyrrolidin-1-yl)-benzooxazol-5-yl]-3-(4-fluoro-phenyl)-acrylamide

반응식

[CH3:19][N:20]([CH:21]1[CH2:22][N:23]([c:26]2[o:27][c:28]3[c:29]([n:30]2)[cH:31][c:32]([NH2:35])[cH:33][cH:34]3)[CH2:24][CH2:25]1)[CH3:36].[Cl:13][C:14]([C:15]([Cl:16])=[O:17])=[O:18].[F:1][c:2]1[cH:3][cH:4][c:5]([CH:6]=[CH:7][C:8](=[O:9])[OH:10])[cH:11][cH:12]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:6]=[CH:7][C:8](=[O:10])[NH:35][c:32]2[cH:31][c:29]3[c:28]([o:27][c:26]([N:23]4[CH2:22][CH:21]([N:20]([CH3:19])[CH3:36])[CH2:25][CH2:24]4)[n:30]3)[cH:34][cH:33]2)[cH:11][cH:12]1

참가 물질

반응물 3

HCID 65578Oxalyl chloride

HCID 980703-(4-Fluorophenyl)-2-propenoic acid

HCID 687717302-(3-Dimethylamino-pyrrolidin-1-yl)-benzooxazol-5-ylamine

생성물 1

HCID 68770527N-[2-(3-Dimethylamino-pyrrolidin-1-yl)-benzooxazol-5-yl]-3-(4-fluoro-phenyl)-acrylamide

출처 및 근거

ORD 기록: ord-5b6528adc4864723a5690f1e59da72f7
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…