2,4-Dichlorobenzylidenemalononitrile → 5-(Aminomethyl)-6-(2,4-dichlorophenyl)-2-(4-methoxyphenyl)pyrimidin-4-amine

HRID 1793908

반응식

HRID 1793908 반응식
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([NH2:9])=[NH:8])=[CH:5][CH:4]=1.[Cl:12][C:13]1[CH:24]=[C:23]([Cl:25])[CH:22]=[CH:21][C:14]=1[CH:15]=[C:16]([C:19]#[N:20])[C:17]#[N:18]>>[NH2:20][CH2:19][C:16]1[C:17]([NH2:18])=[N:8][C:7]([C:6]2[CH:10]=[CH:11][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)=[N:9][C:15]=1[C:14]1[CH:21]=[CH:22][C:23]([Cl:25])=[CH:24][C:13]=1[Cl:12]

참가 물질

3

반응물 2

HCID 180892,4-DichlorobenzylidenemalononitrileHCID 2290744-Methoxybenzenecarboximidamide

생성물 1

HCID 101726015-(Aminomethyl)-6-(2,4-dichlorophenyl)-2-(4-methoxyphenyl)pyrimidin-4-amine

실험 절차

The title compound, MS: m/e=375.3 (M+H+), was prepared from 4-methoxybenzamidine and 2-(2,4-dichloro-benzylidene)-malononitrile in analogy to the process described in Example 11 as a solid.

출처 및 근거

ORD 기록
ord-99056677fffe4e6c86195c2b44cd2722
출처 데이터셋
uspto-grants-2006_04
특허 번호
US07022718B2

연결된 노트

불러오는 중…