HCID 10157588, 화합물 → (10,11-Dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-10-yl)-[4-(3-hydroxy-cyclohex-1-en-1-yl)-3-methyl-phenyl]-methanone
반응식
[CH:1]1[CH:2]=[CH:3][N:4]2[CH2:10][C:9]3[CH:11]=[CH:12][CH:13]=[CH:14][C:8]=3[N:7]([C:15]([C:17]3[CH:22]=[CH:21][C:20]([C:23]4[CH2:28][CH2:27][CH2:26][C:25](=[O:29])[CH:24]=4)=[C:19]([CH3:30])[CH:18]=3)=[O:16])[CH2:6][C:5]=12>C(OCC)C>[CH:1]1[CH:2]=[CH:3][N:4]2[CH2:10][C:9]3[CH:11]=[CH:12][CH:13]=[CH:14][C:8]=3[N:7]([C:15]([C:17]3[CH:22]=[CH:21][C:20]([C:23]4[CH2:28][CH2:27][CH2:26][CH:25]([OH:29])[CH:24]=4)=[C:19]([CH3:30])[CH:18]=3)=[O:16])[CH2:6][C:5]=12참가 물질
3
실험 절차
3-[4-(10,11-Dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-10-carbonyl)-2-methyl-phenyl]-cyclohex-2-enone of Example 39 (0.100 g, 0.252 mmol) was reacted in the manner of Example 25. The crude product was dissolved in boiling diethyl ether, filtered and the product precipitated from the filtrate by addition of pentane to provide the title compound (0.100 g) as a white solid.