N,N-dimethyl-2-(piperazin-1-yl)acetamide → HCID 69642397, 화합물

반응식

[CH3:1][N:2]([CH3:12])[C:3](=[O:11])[CH2:4][N:5]1[CH2:10][CH2:9][NH:8][CH2:7][CH2:6]1.[ClH:13].[CH3:14][O:15][C:16]1[C:24]2[O:23][C:22](C)(C)C[C:20]=2[C:19]([C:27]2[C@@H:36]3[C@@H:31]([CH2:32][CH:33]=[CH:34][CH2:35]3)[C:30](=[O:37])[N:29]([C:38]3[CH:43]=[CH:42][C:41]([C:44](N4CCN(C/C=C/C5C=CC=CC=5)CC4)=[O:45])=[CH:40][CH:39]=3)[N:28]=2)=[CH:18][CH:17]=1>>[ClH:13].[CH3:22][O:23][C:24]1[CH:20]=[C:19]([C:27]2[C@@H:36]3[C@@H:31]([CH2:32][CH:33]=[CH:34][CH2:35]3)[C:30](=[O:37])[N:29]([C:38]3[CH:39]=[CH:40][C:41]([C:44]([N:8]4[CH2:7][CH2:6][N:5]([CH2:4][C:3]([N:2]([CH3:12])[CH3:1])=[O:11])[CH2:10][CH2:9]4)=[O:45])=[CH:42][CH:43]=3)[N:28]=2)[CH:18]=[CH:17][C:16]=1[O:15][CH3:14]

참가 물질

반응물 2

HCID 2758642N,N-dimethyl-2-(piperazin-1-yl)acetamide

HCID 69642098HCID 69642098, 화합물

생성물 1

HCID 69642397HCID 69642397, 화합물

실험 절차

Prepared from intermediate product A6 and N,N-dimethyl-2-piperazin-1-yl-acetamide as described for compound 8. M.p. 93–94° C.

출처 및 근거

ORD 기록: ord-c232a6ae20ba41408cc1632a804e798d
출처 데이터셋: uspto-grants-2006_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07022696B2

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