HCID 12088903, 화합물 → 4-Isopropyl-6-methoxy-1,1,7-trimethyl-1,2-dihydronaphthalene

반응식

[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([C:7]([CH3:15])([CH3:14])[CH2:8][CH2:9][C:10]2=O)=[CH:5][C:4]=1[CH3:16].[CH:17]([Mg]Cl)([CH3:19])[CH3:18]>>[CH:17]([C:10]1[C:11]2[C:6](=[CH:5][C:4]([CH3:16])=[C:3]([O:2][CH3:1])[CH:12]=2)[C:7]([CH3:15])([CH3:14])[CH2:8][CH:9]=1)([CH3:19])[CH3:18]

참가 물질

반응물 2

HCID 12088903HCID 12088903, 화합물2회

HCID 178418918HCID 178418918, 화합물

생성물 1

HCID 222182254-Isopropyl-6-methoxy-1,1,7-trimethyl-1,2-dihydronaphthalene수율 100%

실험 절차

Following General Procedure A, 7-methoxy4,4,6-trimethyl-3,4-dihydro-2H-naphthalen-1-one (Compound 6, 1.0 g, 4.6 mmol) was reacted with a solution of 2 M isopropylmagnesium chloride (12 mL, 22.9 mmol) to give 1.1 g (100%) of the title product as a yellow oil.

출처 및 근거

ORD 기록: ord-13b49989cbb24ab3ab018be65c59a196
출처 데이터셋: uspto-grants-2006_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07026487B2

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