Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → 2-Amino-1-oxazolo[4,5-b]pyridin-2-yl-butan-1-ol TFA salt
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | (S)-[1-(hydroxy-oxazolo[4,5-b]pyridin-2-yl-methyl)-propyl]-carbamic acid tert-butyl ester | HCID 21048468 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-Amino-1-oxazolo[4,5-b]pyridin-2-yl-butan-1-ol TFA salt | HCID 86588339 | — |
반응 단계
(S)-[1-(Hydroxy-oxazolo[4,5-b]pyridin-2-yl-methyl)-propyl]-carbamic acid tert-butyl ester (311 mg, 1 mmol) and MeCl2 (5 ml) were mixed and TFA (1 ml) was added at room temperature. After stirring for 1 hour, the solvent and excess TFA were removed under vacuum to produce 355 mg of 2-Amino-1-oxazolo[4,5-b]pyridin-2-yl-butan-1-ol TFA salt.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07030116B2 |
| 출처 데이터셋 | uspto-grants-2006_04 |
| ORD ID | ord-d901b6c8fd29471daa906a9c3c9733c2 |
| 출처 메모 | uspto-grants-2006_04 |