3-Benzylsulfonyl-2-(tetrahydro-pyran-4-yloxymethyl)-propionic acid → 3-Phenylmethanesulfonyl-n-[(s)-1-(5-phenyl-1,2,4-oxadiazole-3-carbonyl)-propyl]-2-(tetrahydro-pyran-4-yloxymethyl)-propionamide
반응식
[C:1]1([CH2:7][S:8]([CH2:11][CH:12]([CH2:16][O:17][CH:18]2[CH2:23][CH2:22][O:21][CH2:20][CH2:19]2)[C:13]([OH:15])=O)(=[O:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:24][CH:25]([CH2:39][CH3:40])[C@@H:26]([C:28]1[N:32]=[C:31]([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[O:30][N:29]=1)[OH:27]>>[C:1]1([CH2:7][S:8]([CH2:11][CH:12]([CH2:16][O:17][CH:18]2[CH2:23][CH2:22][O:21][CH2:20][CH2:19]2)[C:13]([NH:24][C@H:25]([C:26]([C:28]2[N:32]=[C:31]([C:33]3[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=3)[O:30][N:29]=2)=[O:27])[CH2:39][CH3:40])=[O:15])(=[O:9])=[O:10])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1참가 물질
3
실험 절차
It is similarly prepared according to general procedure given for Example 1 above but using 2-Phenylmethanesulfonylmethyl-3-(tetrahydro-pyran-4-yloxy)-propionic acid and (S)-2-amino-1-(5-phenyl-1,2,4-oxadiazol-3-yl)-butan-1-ol.
후처리
- customIt is similarly prepared