TFA acetonitrile → 6-(1-Hydroxy-1-methyl-ethyl)-5-methoxy-4-(4-phenoxy-phenylamino)-pyrrolo[1,2-b]pyridazine-3-carbonitrile

반응식

[CH2:1]([O:3]C(C1C(OC)=C2C(NC3C=CC(OC4C=CC=CC=4)=CC=3)=C(C#N)C=NN2C=1)=O)C.[OH:33][C:34]([C:37]1[C:38](C)=[C:39]2[C:44]([NH:45][C:46]3[CH:51]=[CH:50][C:49]([O:52][C:53]4[CH:58]=[CH:57][CH:56]=[CH:55][CH:54]=4)=[CH:48][CH:47]=3)=[C:43]([C:59]#[N:60])[CH:42]=[N:41][N:40]2[CH:61]=1)([CH3:36])[CH3:35].C(O)(C(F)(F)F)=O.O.C(O)(C(F)(F)F)=O.CC#N>>[OH:33][C:34]([C:37]1[C:38]([O:3][CH3:1])=[C:39]2[C:44]([NH:45][C:46]3[CH:47]=[CH:48][C:49]([O:52][C:53]4[CH:58]=[CH:57][CH:56]=[CH:55][CH:54]=4)=[CH:50][CH:51]=3)=[C:43]([C:59]#[N:60])[CH:42]=[N:41][N:40]2[CH:61]=1)([CH3:36])[CH3:35]