p-Acetamidobenzoic acid → 3-Acetylamino-N-{3-cyano-4-[5-(2-methoxy-phenoxy)-pyridin-2-ylamino]-5-methyl-pyrrolo[1,2-b]pyridazin-6-yl}-benzamide

반응식

Cl.[NH2:2]C1C(C)=C2C(NC3C=CC(OC4C=CC=CC=4OC)=CC=3)=C(C#N)C=NN2C=1.C(NC1C=CC(C(O)=O)=CC=1)(=O)C.[C:44]([NH:47][C:48]1[CH:49]=[C:50]([CH:82]=[CH:83][CH:84]=1)[C:51]([NH:53][C:54]1[C:55]([CH3:81])=[C:56]2[C:61]([NH:62][C:63]3[CH:68]=[CH:67][C:66]([O:69][C:70]4[CH:75]=[CH:74][CH:73]=[CH:72][C:71]=4[O:76][CH3:77])=[CH:65]C=3)=[C:60]([C:78]#[N:79])[CH:59]=[N:58][N:57]2[CH:80]=1)=[O:52])(=[O:46])[CH3:45]>>[C:44]([NH:47][C:48]1[CH:49]=[C:50]([CH:82]=[CH:83][CH:84]=1)[C:51]([NH:53][C:54]1[C:55]([CH3:81])=[C:56]2[C:61]([NH:62][C:63]3[CH:68]=[CH:67][C:66]([O:69][C:70]4[CH:75]=[CH:74][CH:73]=[CH:72][C:71]=4[O:76][CH3:77])=[CH:65][N:2]=3)=[C:60]([C:78]#[N:79])[CH:59]=[N:58][N:57]2[CH:80]=1)=[O:52])(=[O:46])[CH3:45]