Methylamine → 1,5-Dimethylpyrrolidin-2-one

HRID 1796695

반응식

HRID 1796695 반응식
[CH3:1][C:2]1[O:7][C:5](=[O:6])[CH2:4][CH:3]=1.[CH3:8][NH2:9]>>[CH2:1]=[C:2]1[N:9]([CH3:8])[C:5](=[O:7])[CH2:4][CH2:3]1.[CH3:8][N:9]1[CH:2]([CH3:1])[CH2:3][CH2:4][C:5]1=[O:6]

참가 물질

4

반응물 2

HCID 6329MethylamineHCID 11559alpha-Angelica lactone

생성물 2

HCID 1011941,5-Dimethylpyrrolidin-2-oneHCID 13462148HCID 13462148, 화합물

실험 절차

Wedler, et al. (Journal. f. prakt. Chemie (1990) 332:557–562) discuss a process for producing 5-hydroxy-1,5-dimethyl-2-pyrrolidone by reacting α-angelica lactone with methylamine. Dehydration of this product resulted in the formation of the unstable 5-methylene-N-methyl-2-pyrrolidone, rather than the desired 1,5-dimethyl-2-pyrrolidone.

출처 및 근거

ORD 기록
ord-1045b4d2557a44dbbd01acf61a1aed1c
출처 데이터셋
uspto-grants-2006_04
특허 번호
US07030249B2

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