Tetrahydrofuran → 1-Methoxyoct-2-ene

HRID 1796847

반응식

HRID 1796847 반응식
[CH3:1][O:2][CH2:3][CH:4]=[CH:5][CH2:6][CH2:7][CH2:8][CH:9]=[CH2:10].O1CCCC1.[H][H]>C1C=CC(P(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.C1C=CC(P(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.C1C=CC(P(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.[Cl-].[Cl-].[Ru+2].C(O)C>[CH3:1][O:2][CH2:3][CH:4]=[CH:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

참가 물질

6

반응물 3

HCID 8028TetrahydrofuranHCID 5350261-Methoxy-2,7-octadiene2회HCID 178418361HCID 178418361, 화합물2회

생성물 1

HCID 540099991-Methoxyoct-2-ene

시약·촉매·용매 2

HCID 84971Tris(triphenylphosphine)ruthenium(II) dichloride촉매HCID 702Ethanol용매

실험 절차

1000 g of 1-methoxy-2,7-octadiene, 500 ml of tetrahydrofuran, 500 ml of ethanol and 2.5 g of tris(triphenylphosphine)ruthenium(II) chloride were placed in a 3 l Büchi autoclave. The temperature was set to 30° C. and the autoclave was pressurized to 30 bar by means of hydrogen. The reaction was followed via the amount of hydrogen taken up and by means of GC analyses. After 6 hours, the reaction was stopped. According to GC analysis, 98% of the 1-methoxy-2,7-octadiene had reacted to form 1-methoxy-2-octene (cis and trans) with a selectivity of 89%. The 1-methoxy-2-octene was separated from solvents and catalyst by distillation.

후처리

  1. customwas set to 30° C.
  2. customhad reacted

출처 및 근거

ORD 기록
ord-feb857e726424950acdea963b88e41cc
출처 데이터셋
uspto-grants-2006_04
특허 번호
US07030286B2

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