4-(2-Cyclopropylethoxy)-n-((z)-2-(4-ethoxyphenyl)-1-{[(2-hydroxyethyl)amino]carbonyl}vinyl)benzamide → 4-(2-Cyclopropylethoxy)-n-{1-(4-ethoxybenzyl)-2-[(2-hydroxyethyl)amino]-2-oxoethyl}benzamide
반응식
C1(CCOC2C=CC(C(NC(CC3C=CC(CCC)=CC=3)C(NCCO)=O)=O)=CC=2)CC1.[CH:33]1([CH2:36][CH2:37][O:38][C:39]2[CH:64]=[CH:63][C:42]([C:43]([NH:45]/[C:46](/[C:57]([NH:59][CH2:60][CH2:61][OH:62])=[O:58])=[CH:47]\[C:48]3[CH:53]=[CH:52][C:51]([O:54][CH2:55][CH3:56])=[CH:50][CH:49]=3)=[O:44])=[CH:41][CH:40]=2)[CH2:35][CH2:34]1>>[CH:33]1([CH2:36][CH2:37][O:38][C:39]2[CH:64]=[CH:63][C:42]([C:43]([NH:45][CH:46]([CH2:47][C:48]3[CH:53]=[CH:52][C:51]([O:54][CH2:55][CH3:56])=[CH:50][CH:49]=3)[C:57]([NH:59][CH2:60][CH2:61][OH:62])=[O:58])=[O:44])=[CH:41][CH:40]=2)[CH2:35][CH2:34]1참가 물질
3
반응물 2
생성물 1
실험 절차
A reaction similar to that described in Example (1 (1e) was conducted using 4-(2-cyclopropylethoxy)-N-((Z)-2-(4-ethoxyphenyl)-1-{[(2-hydroxyethyl)amino]carbonyl}vinyl)benzamide (197 mg) to give 58 mg of the title compound (white powder).