Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(3,3,3-Trifluoropropoxy)benzoic acid → 2-[((2S)-3-[4-(Trifluoromethoxy)phenyl]-2-{[4-(3,3,3-trifluoropropoxy)benzoyl]amino}propanoyl)amino]ethyl acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(3,3,3-Trifluoropropoxy)benzoic acid | HCID 58111655 | — |
| 반응물 | 2-({(2S)-2-amino-3-[4-(trifluoromethoxy)phenyl]propanoyl}amino)ethyl acetate | HCID 69017543 | — |
| 생성물 | 2-[((2S)-3-[4-(Trifluoromethoxy)phenyl]-2-{[4-(3,3,3-trifluoropropoxy)benzoyl]amino}propanoyl)amino]ethyl acetate | HCID 86636528 | — |
반응 단계
A reaction similar to that described in Example 50 was conducted using 2-({(2S)-2-amino-3-[4-(trifluoromethoxy)phenyl]propanoyl}amino)ethyl acetate and 4-(3,3,3-trifluoropropoxy)benzoic acid obtained in the preparation process of Example 33 (33a) to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08344029B2 |
| 출처 데이터셋 | uspto-grants-2013_01 |
| ORD ID | ord-51dd829be42c434d97bbd61c8335b8b7 |
| 출처 메모 | uspto-grants-2013_01 |