반응식
[F:1][C:2]([F:32])([F:31])[O:3][C:4]1[CH:9]=[CH:8][C:7]([CH2:10][CH:11]([NH:15][C:16](=[O:30])[C:17]2[CH:22]=[CH:21][C:20]([O:23][CH2:24][CH2:25][C:26]([F:29])([F:28])[F:27])=[CH:19][CH:18]=2)[C:12](O)=[O:13])=[CH:6][CH:5]=1.[NH3:33]>>[NH2:33][C:12](=[O:13])[CH:11]([NH:15][C:16](=[O:30])[C:17]1[CH:22]=[CH:21][C:20]([O:23][CH2:24][CH2:25][C:26]([F:29])([F:28])[F:27])=[CH:19][CH:18]=1)[CH2:10][C:7]1[CH:8]=[CH:9][C:4]([O:3][C:2]([F:32])([F:31])[F:1])=[CH:5][CH:6]=1참가 물질
3
실험 절차
A reaction similar to that described in Example 32 (32c) was conducted using 3-[4-(trifluoromethoxy)phenyl]-2-{[4-(3,3,3-trifluoropropoxy)benzoyl]amino}propanoic acid (5.00 g) prepared in Example 70 (70a) and ammonia (16.1 mL, 2 M ethanol solution) to give 4.51 g of the title compound (white powder).
후처리
- customA reaction similar to
출처 및 근거
- ORD 기록
- ord-c9c6085cd3064732b380c37779ec2ad2
- 출처 데이터셋
- uspto-grants-2013_01
- 특허 번호
- US08344029B2
연결된 노트
불러오는 중…