Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-3-[4-(trifluoromethoxy)phenyl]propanoic acid hydrochloride → 2-{[2-Fluoro-4-(3,3,3-trifluoropropoxy)benzoyl]amino}-3-[4-(trifluoromethoxy)phenyl]propanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-3-[4-(trifluoromethoxy)phenyl]propanoic acid hydrochloride | HCID 22603340 | — |
| 반응물 | 2-Fluoro-4-(3,3,3-trifluoropropoxy)benzoic acid | HCID 69019004 | — |
| 생성물 | 2-{[2-Fluoro-4-(3,3,3-trifluoropropoxy)benzoyl]amino}-3-[4-(trifluoromethoxy)phenyl]propanoic acid | HCID 87657675 | 93.7% |
반응 단계
A reaction similar to that described in Example 70 (70a) was conducted using 2-fluoro-4-(3,3,3-trifluoropropoxy)benzoic acid (177 mg) prepared in Example 84 (84a) and 2-amino-3-[4-(trifluoromethoxy)phenyl]propanoic acid hydrochloride (200 mg) prepared in Reference Example 2 to give 317 mg of the title compound (white powder).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08344029B2 |
| 출처 데이터셋 | uspto-grants-2013_01 |
| ORD ID | ord-16f7d383c3bd46be9e793895133f6427 |
| 출처 메모 | uspto-grants-2013_01 |