3-Pyridinemethanamine → 2-(1-(4-(difluoromethoxy)benzyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)-4-methyl-N-(pyridin-3-ylmethyl)thiazole-5-carboxamide

반응식

[CH3:1][c:2]1[n:3][c:4](-[n:5]2[c:6](=[O:7])[n:8]([CH2:9][c:10]3[cH:11][cH:12][c:13]([C:14]([F:15])([F:16])[F:17])[cH:18][cH:19]3)[n:20][cH:21]2)[s:22][c:23]1[C:24]([OH:25])=[O:26].[F:27][CH:28]([O:29][c:30]1[cH:31][cH:32][c:33]([CH2:34][n:35]2[n:36][cH:37][n:38](-[c:41]3[s:42][c:43]([C:47](=[O:48])[OH:49])[c:44]([CH3:46])[n:45]3)[c:39]2=[O:40])[cH:50][cH:51]1)[F:52].[n:53]1[cH:54][c:55]([CH2:59][NH2:60])[cH:56][cH:57][cH:58]1>>[F:27][CH:28]([O:29][c:30]1[cH:31][cH:32][c:33]([CH2:34][n:35]2[n:36][cH:37][n:38](-[c:41]3[s:42][c:43]([C:47](=[O:48])[NH:60][CH2:59][c:55]4[cH:54][n:53][cH:58][cH:57][cH:56]4)[c:44]([CH3:46])[n:45]3)[c:39]2=[O:40])[cH:50][cH:51]1)[F:52]