5-Fluoro-2-methoxyphenylboronic acid → 3-Chlorophenyl 2,5'-difluoro-2'-methoxybiphenyl-4-yl sulfone

HRID 1802871

반응식

HRID 1802871 반응식
Br[C:2]1[CH:7]=[CH:6][C:5]([S:8]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([Cl:17])[CH:12]=2)(=[O:10])=[O:9])=[CH:4][C:3]=1[F:18].[F:19][C:20]1[CH:21]=[CH:22][C:23]([O:29][CH3:30])=[C:24](B(O)O)[CH:25]=1>>[F:18][C:3]1[CH:4]=[C:5]([S:8]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([Cl:17])[CH:12]=2)(=[O:10])=[O:9])[CH:6]=[CH:7][C:2]=1[C:22]1[CH:21]=[C:20]([F:19])[CH:25]=[CH:24][C:23]=1[O:29][CH3:30]

참가 물질

3

반응물 2

HCID 27826735-Fluoro-2-methoxyphenylboronic acidHCID 67239474HCID 67239474, 화합물

생성물 1

HCID 672393053-Chlorophenyl 2,5'-difluoro-2'-methoxybiphenyl-4-yl sulfone

실험 절차

The subtitle compound was prepared by the method of example 2 step (ii) using the product of step (ii) and 5-fluoro-2-methoxybenzene boronic acid.

출처 및 근거

ORD 기록
ord-c2e5192a190346dc98a4f208b420af0c
출처 데이터셋
uspto-grants-2013_01
특허 번호
US08349897B2

연결된 노트

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