Triethylamine → HCID 54192011, 화합물

HRID 1803060노트

반응식

HRID 1803060 반응식
[NH2:1][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1.[CH2:9](N(CC)CC)[CH3:10]>C1COCC1>[CH:2]1[N:1]=[CH:10][CH2:9][N:4]2[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=12

참가 물질

4

반응물 2

HCID 8471TriethylamineHCID 195092-Pyridinemethanamine

생성물 1

HCID 54192011HCID 54192011, 화합물

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

2-aminomethyl pyridine (10 mmol) was dissolved together with triethylamine (20 mmol) in THF (50 ml) and a solution of the corresponding bis-imidoylchloride (10 mmol) was added dropwise. Then the solution was refluxed for ca. 4 h and after cooling-down the solvent was removed under reduced pressure. The residue was washed with little cold methanol and subsequently, the residue was recrystallized from acetonitrile or THF.

후처리

  1. temperatureThen the solution was refluxed for ca. 4 h
  2. temperatureafter cooling-down the solvent
  3. customwas removed under reduced pressure
  4. washThe residue was washed with little cold methanol
  5. customsubsequently, the residue was recrystallized from acetonitrile or THF

출처 및 근거

ORD 기록
ord-78cd227edabb4a47b9ff21c79ea7bae2
출처 데이터셋
uspto-grants-2013_01
특허 번호
US08350038B2

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