Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → 1-(3-Methoxy-4-(6-methylpyridazin-4-yl)phenyl)thiourea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | 5-(4-Isothiocyanato-2-methoxyphenyl)-3-methylpyridazine | HCID 86649909 | — |
| 생성물 | 1-(3-Methoxy-4-(6-methylpyridazin-4-yl)phenyl)thiourea | HCID 86649910 | 100% |
반응 단계
Step L (5): Methanolic ammonia (2.0 M, 20 mL, 40 mmol) was added to a flask charged with 5-(4-isothiocyanato-2-methoxyphenyl)-3-methylpyridazine (650 mg, 2.53 mmol). After 4 h, the reaction mixture was concentrated in vacuo to afford 1-(3-methoxy-4-(6-methylpyridazin-4-yl)phenyl)thiourea (690 mg, 100% yield). LC-MS (M+H)+ 275.2.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08349880B2 |
| 출처 데이터셋 | uspto-grants-2013_01 |
| ORD ID | ord-b0c012bd691049399497d45dcccf01d8 |
| 출처 메모 | uspto-grants-2013_01 |