Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Bromo-2-fluorobenzoyl chloride → (4-Bromo-2-fluorophenyl)[4-(3,5-dimethylpyrazin-2-yl)piperazin-1-yl]methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Bromo-2-fluorobenzoyl chloride | HCID 2734026 | — |
| 반응물 | (3,5-Dimethylpyrazin-2-yl)piperazine hydrochloride | HCID 67381341 | — |
| 생성물 | (4-Bromo-2-fluorophenyl)[4-(3,5-dimethylpyrazin-2-yl)piperazin-1-yl]methanone | HCID 58484696 | 69.9% |
반응 단계
By reaction and treatment in the same manner as in Preparation Example 8 and using 4-bromo-2-fluorobenzoyl chloride (1.1 g) and 1-(3,5-dimethylpyrazin-2-yl)piperazine hydrochloride (915 mg) described in Preparation Example 59, the title compound (1.1 g) was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08354401B2 |
| 출처 데이터셋 | uspto-grants-2013_01 |
| ORD ID | ord-4cd6e7e1f65a44afb88ec664acedf589 |
| 출처 메모 | uspto-grants-2013_01 |