Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Bromo-2-fluorobenzoic acid → (4-Bromo-2-fluorophenyl)[4-(5-methylpyridin-2-yl)piperazin-1-yl]methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Bromo-2-fluorobenzoic acid | HCID 302681 | — |
| 반응물 | 1-(5-Methyl-2-pyridinyl)piperazine | HCID 11480779 | — |
| 생성물 | (4-Bromo-2-fluorophenyl)[4-(5-methylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484600 | 88.9% |
반응 단계
By reaction and treatment in the same manner as in Preparation Example 90 and using 4-bromo-2-fluorobenzoic acid (1.45 g) and 1-(5-methylpyridin-2-yl)piperazine (1.06 g) described in Preparation Example 183, the title compound (2.01 g) was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08354401B2 |
| 출처 데이터셋 | uspto-grants-2013_01 |
| ORD ID | ord-473bee038c0a495ea5ae79571b1e382e |
| 출처 메모 | uspto-grants-2013_01 |