2-Oxazolidinone → HCID 67381093, 화합물

HRID 1804148

반응식

HRID 1804148 반응식
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[N:9]1[CH2:14][CH2:13][N:12]([C:15]([C:17]2[CH:22]=[CH:21][C:20](I)=[CH:19][CH:18]=2)=[O:16])[CH2:11][CH2:10]1.[O:24]1[CH2:28][CH2:27][NH:26][C:25]1=[O:29]>>[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[N:9]1[CH2:14][CH2:13][N:12]([C:15]([C:17]2[CH:22]=[CH:21][C:20]([N:26]3[CH2:27][CH2:28][O:24][C:25]3=[O:29])=[CH:19][CH:18]=2)=[O:16])[CH2:11][CH2:10]1

참가 물질

3

반응물 2

HCID 739492-OxazolidinoneHCID 58484733[4-(2,4-Dimethylphenyl)piperazin-1-yl](4-iodophenyl)methanone

생성물 1

HCID 67381093HCID 67381093, 화합물수율 57.5%

실험 절차

By reaction and treatment in the same manner as in Example 1 and using [4-(2,4-dimethylphenyl)piperazin-1-yl](4-iodophenyl)methanone (7.7 g) described in Preparation Example 8 and oxazolidin-2-one (1.6 g), the title compound (4 g) was obtained.

후처리

  1. customBy reaction and treatment in the same manner as in Example 1

출처 및 근거

ORD 기록
ord-8a7122117b0a4ca081e95aa50d0b5534
출처 데이터셋
uspto-grants-2013_01
특허 번호
US08354401B2

연결된 노트

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