Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(4R)-4-tert-Butyl-1,3-oxazolidin-2-one → 4-Tert-butyl-3-{4-[4-(2,4-dimethylphenyl)piperazine-1-carbonyl]-3-methanesulfonylphenyl}oxazolidin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (4R)-4-tert-Butyl-1,3-oxazolidin-2-one | HCID 2734860 | — |
| 반응물 | (4-Bromo-2-methanesulfonylphenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone | HCID 58484856 | — |
| 생성물 | 4-Tert-butyl-3-{4-[4-(2,4-dimethylphenyl)piperazine-1-carbonyl]-3-methanesulfonylphenyl}oxazolidin-2-one | HCID 67381400 | 0.9% |
반응 단계
By reaction and treatment in the same manner as in Example 1 and using (4-bromo-2-methanesulfonylphenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone (903 mg) described in Preparation Example 9 and (R)-4-tert-butyloxazolidin-2-one (286 mg), the title compound (9 mg) was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08354401B2 |
| 출처 데이터셋 | uspto-grants-2013_01 |
| ORD ID | ord-1df7eed66a4a4adaba3f6c3216cb1f16 |
| 출처 메모 | uspto-grants-2013_01 |