tert-Butyl piperazine-1-carboxylate → Tert-butyl 4-(pyridin-2-ylmethyl)piperazine-1-carboxylate

HRID 1804629노트

반응식

HRID 1804629 반응식
Br[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1.[N:9]1([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]1>>[N:4]1[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=1[CH2:2][N:12]1[CH2:11][CH2:10][N:9]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[CH2:14][CH2:13]1

참가 물질

3

반응물 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 5642092-(Bromomethyl)pyridine

생성물 1

HCID 10062065Tert-butyl 4-(pyridin-2-ylmethyl)piperazine-1-carboxylate

실험 절차

Prepared from 2-(bromomethyl)pyridine and tert-butyl 1-piperazine-carboxylate using the procedure described in Step A of Intermediate 113. LC/MS: m/z (ES) 278.1 (MH)+.

출처 및 근거

ORD 기록
ord-02da9516dbee4b4aa65d6b12ad249001
출처 데이터셋
uspto-grants-2013_01
특허 번호
US08354403B2

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