3-(Trifluoromethoxy)benzoyl chloride → N-(3-(2-methyl-3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenyl)-3-(trifluoromethoxy)benzamide

반응식

[F:21][C:22]([O:23][c:24]1[cH:25][c:26]([C:27](=[O:28])[Cl:29])[cH:30][cH:31][cH:32]1)([F:33])[F:34].[NH2:1][c:2]1[cH:3][c:4]([O:5][c:6]2[cH:7][cH:8][n:9][c:10]3[nH:11][c:12](=[O:17])[c:13]([CH3:16])[n:14][c:15]23)[cH:18][cH:19][cH:20]1>>[NH:1]([c:2]1[cH:3][c:4]([O:5][c:6]2[cH:7][cH:8][n:9][c:10]3[nH:11][c:12](=[O:17])[c:13]([CH3:16])[n:14][c:15]23)[cH:18][cH:19][cH:20]1)[C:27]([c:26]1[cH:25][c:24]([O:23][C:22]([F:21])([F:33])[F:34])[cH:32][cH:31][cH:30]1)=[O:28]

참가 물질

반응물 2

HCID 5228543-(Trifluoromethoxy)benzoyl chloride

HCID 469015948-(3-aminophenoxy)-2-methylpyrido[2,3-b]pyrazin-3(4H)-one

생성물 1

HCID 44133723N-(3-(2-methyl-3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenyl)-3-(trifluoromethoxy)benzamide

출처 및 근거

ORD 기록: ord-807d5df831434b9fabaa42464ac28754
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

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