2-Methoxyphenethyl alcohol → 4-[2-(2-methoxy-phenyl)-ethoxy]-1H-indole-2-carboxylic acid

HRID 1804777노트

반응식

HRID 1804777 반응식
C1(CO[C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH:9]=[C:10]([C:16]([OH:18])=[O:17])[NH:11]3)CCC1.[CH3:19][O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[CH2:27][CH2:28][OH:29].C(OC(C1NC2C(C=1)=C(O)C=CC=2)=O)C>>[CH3:19][O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[CH2:27][CH2:28][O:29][C:7]1[CH:15]=[CH:14][CH:13]=[C:12]2[C:8]=1[CH:9]=[C:10]([C:16]([OH:18])=[O:17])[NH:11]2

참가 물질

4

반응물 3

HCID 819092-Methoxyphenethyl alcoholHCID 13274763Ethyl 4-hydroxy-1H-indole-2-carboxylateHCID 591526824-Cyclobutylmethoxy-1H-indole-2-carboxylic acid

생성물 1

HCID 591526474-[2-(2-methoxy-phenyl)-ethoxy]-1H-indole-2-carboxylic acid

실험 절차

4-[2-(2-Methoxy-phenyl)-ethoxy]-1H-indole-2-carboxylic acid (16j) is synthesized analogous to 16a from 2-(2-methoxy-phenyl)-ethanol and 4-hydroxy-1H-indole-2-carboxylic acid ethyl ester.

출처 및 근거

ORD 기록
ord-a3a24b48548e41c2b6fb56b5782e80de
출처 데이터셋
uspto-grants-2013_01
특허 번호
US08354431B2

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