2-Bromoethyl ethyl ether → 4-[6-(2-Ethoxy-ethoxy)-benzofuran-3-ylmethoxy]-1H-indole-2-carboxylic acid
반응식
[CH2:1]([O:3][C:4]1[CH:26]=[CH:25][C:7]2[C:8]([CH2:11][O:12][C:13]3[CH:21]=[CH:20][CH:19]=[C:18]4[C:14]=3[CH:15]=[C:16]([C:22]([OH:24])=[O:23])[NH:17]4)=[CH:9][O:10][C:6]=2[CH:5]=1)[CH3:2].[CH2:27]([O:29]C(C1C2C=CC(O)=CC=2OC=1)=O)[CH3:28].C(OCCBr)C>>[CH2:27]([O:29][CH2:2][CH2:1][O:3][C:4]1[CH:26]=[CH:25][C:7]2[C:8]([CH2:11][O:12][C:13]3[CH:21]=[CH:20][CH:19]=[C:18]4[C:14]=3[CH:15]=[C:16]([C:22]([OH:24])=[O:23])[NH:17]4)=[CH:9][O:10][C:6]=2[CH:5]=1)[CH3:28]참가 물질
4
실험 절차
4-[6-(2-Ethoxy-ethoxy)-benzofuran-3-ylmethoxy]-1H-indole-2-carboxylic acid (30c) is synthesized analogous to 30a from 6-hydroxy-benzofuran-3-carboxylic acid ethyl ester (26) and 2-bromoethyl ethyl ether.
출처 및 근거
- ORD 기록
- ord-23d533680eeb492ea593c0391abf0b82
- 출처 데이터셋
- uspto-grants-2013_01
- 특허 번호
- US08354431B2
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