Isopropyl iodide → 3-Isopropyl-1H-indol-6-amine
반응식
[N+:1]([C:4]1[CH:12]=[C:11]2[C:7]([CH:8]=[CH:9][NH:10]2)=[CH:6][CH:5]=1)([O-])=O.[CH:13](I)([CH3:15])[CH3:14]>CC#N>[CH:13]([C:8]1[C:7]2[C:11](=[CH:12][C:4]([NH2:1])=[CH:5][CH:6]=2)[NH:10][CH:9]=1)([CH3:15])[CH3:14]참가 물질
4
실험 절차
3-Isopropyl-1H-indol-6-ylamine (B-13) was synthesized following the general scheme above starting from 6-nitroindole and isopropyl iodide. Overall yield (17%). HPLC ret. time 2.06 min, 10-99% CH3CN, 5 min run; ESI-MS 175.2 m/z (MH+).
후처리
- customOverall yield (17%)
출처 및 근거
- ORD 기록
- ord-dc1198163f6e48eba1ab71d4d9511f79
- 출처 데이터셋
- uspto-grants-2013_01
- 특허 번호
- US08354427B2
반응 노트
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