Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Cyanide → 2-(4-Chloro-2-methoxyphenyl)acetonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Cyanide | HCID 8929 | — |
| 반응물 | 4-Chloro-1-(chloromethyl)-2-methoxybenzene | HCID 18523560 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2-(4-Chloro-2-methoxyphenyl)acetonitrile | HCID 22327524 | 36.7% |
반응 단계
Step B In a manner similar to the method described in Example 57 Step B, 4-chloro-2-methoxybenzyl chloride (5.1 g, 27 mmol) was reacted with NaCN (3 g, 61 mmol) in ethanol (40 mL) and water (20 mL) at 100° C. for 8 h to give 4-chloro-2-methoxybenzyl cyanide as a colorless oil (1.8 g, 36%)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08354444B2 |
| 출처 데이터셋 | uspto-grants-2013_01 |
| ORD ID | ord-63d99f0dddee4c84a99ab6a01ccd95eb |
| 출처 메모 | uspto-grants-2013_01 |