Glycine tert-butyl ester → HCID 178446419, 화합물

HRID 1807008노트

반응식

HRID 1807008 반응식
[C:1]([O:5][C:6](=[O:9])[CH2:7][NH2:8])([CH3:4])([CH3:3])[CH3:2].[N:10]([CH2:13][CH2:14][C:15]([CH3:20])([CH3:19])[CH2:16][CH:17]=O)=[N+:11]=[N-:12]>C(Cl)Cl>[C:1]([O:5][C:6](=[O:9])[CH2:7]/[N:8]=[CH:17]/[CH2:16][C:15]([CH3:20])([CH3:19])[CH2:14][CH2:13][N:10]=[N+:11]=[N-:12])([CH3:4])([CH3:3])[CH3:2]

참가 물질

4

반응물 2

HCID 151417Glycine tert-butyl esterHCID 866404265-Azido-3,3-dimethyl-pentanal

생성물 1

HCID 178446419HCID 178446419, 화합물수율 100%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

Step C In a manner similar to the method described in Example 1a, glycine tert-butyl ester (0.32 g, 2.45 mmol) was reacted with 5-azido-3,3-dimethyl-pentanal (0.38 g, 2.45 mmol) in CH2Cl2 at room temperature for 18 h to give [5-azido-3,3-dimethyl-pent-(E)-ylideneamino]-acetic acid tert-butyl ester as a yellow oil (0.65 g, 100%).

출처 및 근거

ORD 기록
ord-3f6b3d1f27424755946b75790209f91b
출처 데이터셋
uspto-grants-2013_01
특허 번호
US08354444B2

반응 노트

불러오는 중…