Potassium Carbonate → (R)-tert-butyl 4-(2-(3-cyano-4-isopropoxyphenyl)oxazol-5-yl)-2,3-dihydro-1H-inden-1-ylcarbamate

반응식

CC1(C)C(C)(C)OB([C:9]2[CH:17]=[CH:16][CH:15]=[C:14]3[C:10]=2[CH2:11][CH2:12][C@H:13]3[NH:18][C:19](=[O:25])[O:20][C:21]([CH3:24])([CH3:23])[CH3:22])O1.Br[C:28]1[O:32][C:31]([C:33]2[CH:34]=[CH:35][C:36]([O:41][CH:42]([CH3:44])[CH3:43])=[C:37]([CH:40]=2)[C:38]#[N:39])=[N:30][CH:29]=1.C(=O)([O-])[O-].[K+].[K+].CC(O)C(O)C.O>>[C:38]([C:37]1[CH:40]=[C:33]([C:31]2[O:32][C:28]([C:9]3[CH:17]=[CH:16][CH:15]=[C:14]4[C:10]=3[CH2:11][CH2:12][C@H:13]4[NH:18][C:19](=[O:25])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])=[CH:29][N:30]=2)[CH:34]=[CH:35][C:36]=1[O:41][CH:42]([CH3:44])[CH3:43])#[N:39]