Imidazole-1-carboxylic acid (8-tert-butyl-4,5-dihydro-thiazolo[4,5-h]quinazolin-2-yl)-amide → Imidazole-1-carboxylic acid (8-methyl-4H-5-oxa-1-thia-3,7-diaza-cyclopenta[a]naphthalen-2-yl)-amide
반응식
[CH3:1][C:2]1[CH:11]=[C:10]2[C:5]([O:6][CH2:7][C:8]3[N:14]=[C:13]([NH:15][C:16](=[O:18])C)[S:12][C:9]=32)=[CH:4][N:3]=1.C(C1N=CC2CCC3N=C(NC([N:39]4[CH:43]=[CH:42][N:41]=[CH:40]4)=O)SC=3C=2N=1)(C)(C)C>>[CH3:1][C:2]1[CH:11]=[C:10]2[C:5]([O:6][CH2:7][C:8]3[N:14]=[C:13]([NH:15][C:16]([N:39]4[CH:43]=[CH:42][N:41]=[CH:40]4)=[O:18])[S:12][C:9]=32)=[CH:4][N:3]=1참가 물질
3
반응물 2
생성물 1
실험 절차
Imidazole-1-carboxylic acid (8-methyl-4H-5-oxa-1-thia-3,7-diaza-cyclopenta[a]naphthalen-2-yl)-amide was prepared from N-(8-methyl-4H-5-oxa-1-thia-3,7-diaza-cyclopenta[a]naphthalen-2-yl)-acetamide (Stage 40.2) using synthetic methodology as described for the preparation of intermediate A.