Chloropyrazine → tert-Butyl 2-((pyrazin-2-ylamino)methyl)piperidine-1-carboxylate

HRID 18081

반응식

HRID 18081 반응식
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH:9]1[CH2:14][NH2:15])=[O:7])([CH3:4])([CH3:3])[CH3:2].Cl[C:17]1[CH:22]=[N:21][CH:20]=[CH:19][N:18]=1>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH:9]1[CH2:14][NH:15][C:17]1[CH:22]=[N:21][CH:20]=[CH:19][N:18]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

참가 물질

3

실험 절차

The title compound (0.18 g) was prepared from (RS) 2-aminomethyl-piperidine-1-carboxylic acid tert butyl ester (0.54 g) and 2-chloropyrazine according to the method of D20.

출처 및 근거

ORD 기록
ord-4bb18f1de9ad42f881952d824f68e301
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07741329B2

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